The invention is represented by a deformable artificial ventricle, able to obtain a cardiac output comparable to that achieved by rigid devices, based on traditional pumping principles. Capable of varying the amount of expelled blood, in both design and post-transplant phases, adapting different patient’s needs. The aim is to provide the full replacement of compromised ventricles, including at least one artificial ventricle by the use of a blood pumping system. The manufacturing method of the device is also incorporated.
Heart failure is a chronic pathological condition occurring when the cardiac muscle is unable to pump enough blood into the cardiovascular system. This pathology can be associated with one of the two ventricles; however, in the worst case, it involves both cardiac ventricles. Heart failure is an extremely serious disease, which strongly affects patient’s survival, and has devastating consequences on his life.
Current Technology Limits
Artificial hearts, capable of achieving physiologically cardiac output, usually are made using rigid materials, characterised by poor biocompatibility and hemocompatibility. The present invention is represented by a soft, biocompatible and hemocompatible device, able to emulate the pumping function of the human ventricle. The device consists of at least one active layer, mechanically connected and wrapped around a passive, concave, and foldable volume.
Our Technology and Solutions
The device consists of an elastomeric ventricular chamber, representing the collapsible volume in contact with the patient’s blood. Integrating a number of active layers, with at least a soft actuator. Substrate of this latter can be made of materials with different mechanical properties.
Advantages are the adaptability and flexibility of the artificial cardiac muscle, due to the use of biocompatible and deformable materials with properties comparable to the myocardial tissue. A damage reduction of the surrounding tissues is also associated.
Cardiac muscle contractile force is adaptable, allowing for an improvement of the pumping efficiency.
The use of the 3D printing simplifies the manufacturing process.